TY - JOUR TI - Stereoselective preparation of chiral compounds in Mannich-type reactions of a bicyclic imine and phenols or indole Dedicated to Professor Jacek Skarzewski on the occasion of his 65th birthday AU - Iwanejko, J. AU - Wojaczyńska, E. AU - Wojaczyński, J. AU - Bąkowicz, J. T2 - Tetrahedron Letters AB - Mannich-type reactions of a chiral bicyclic imine and various nucleophiles yield the corresponding adducts with good to high diastereoselectivity. The influence of the reaction conditions on the yield and stereochemical outcome is investigated. The configuration of the products is established by 1H NMR spectroscopy, and the major isomers of two adducts are characterized by X-ray crystallography. © 2014 Elsevier Ltd. All rights reserved. DA - 2014/// PY - 2014 DO - 10.1016/j.tetlet.2014.10.081 DP - Scopus VL - 55 IS - 49 SP - 6619 EP - 6622 DB - Scopus KW - Betti reaction KW - Bicyclic imines KW - Mannich reaction KW - Stereoselectivity ER -