TY - JOUR TI - A new tool in the toolbox: Electron-withdrawing group activated -Ruthenium Catalysts for Olefin Metathesis AU - Olszewski, T.K. AU - Bieniek, M. AU - Skowerski, K. AU - Grela, K. T2 - Synlett AB - This account describes the discovery and development of efficient electron-withdrawing group activated Hoveyda-Grubbs catalysts, including a nitro-substituted catalyst and their applications in the syntheses of complex molecules. 1 Introduction 2 EWG-Activated Hoveyda-Grubbs Complexes 2.1 The Discovery and the Story Behind It 2.2 The Nitro-Substituted Hoveyda-Grubbs Catalyst 2.3 pH-Responsive Catalysts 2.4 Fine-Tuning of the EWG Fragment 3 Applications of the Nitro-Substituted Hoveyda-Grubbs Catalyst in the Preparation of Compounds of Biological Relevance 3.1 Synthesis of BILN 2061 4 Concluding Remarks. © Georg Thieme Verlag Stuttgart . New York. DA - 2013/// PY - 2013 DO - 10.1055/s-0032-1318497 DP - Scopus VL - 24 IS - 8 ST - A new tool in the toolbox DB - Scopus KW - -organometallic reagents KW - alkenes KW - carbenes KW - catalysis KW - metathesis KW - ruthenium ER -