TY - JOUR TI - Asymmetric synthesis of α-hydroxymethylphosphonates and phosphonic acids via hydrophosphonylation of aldehydes with chiral H-phosphonate AU - Olszewski, T.K. T2 - Tetrahedron Asymmetry AB - Diastereoselective hydrophosphonylation of aldehydes with a chiral H-phosphonate is described. High asymmetric inductions were obtained using a readily available TADDOL auxiliary. Subsequent, racemization-free removal of the chiral auxiliary led to the desired α-hydroxyphosphonic acids in very good yields and high enantiomeric purity as the (R)-enantiomers. © 2015 Elsevier Ltd. All rights reserved. DA - 2015/// PY - 2015 DO - 10.1016/j.tetasy.2015.03.002 DP - Scopus VL - 26 IS - 7 SP - 393 EP - 399 DB - Scopus ER -