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Department of Physical and Quantum Chemistry
Home  >  People  >  Elżbieta Wojaczyńska

Ph.D., D.Sc. Elżbieta Wojaczyńska

Associate Professor, Dean's Plenipotentiary for Promotion

Wybrzeże Wyspiańskiego 27

PL-50370 Wrocław, Poland

elzbieta.wojaczynska@pwr.edu.pl

+48 71 320 2410

Office:Building A02, room 219

Curriculum vitae
Bibliography
Files to download

Scentific interests

Organic chemistry, in particular stereoselective synthesis of mono- and polyheterocyclic systems by hetero-Diels-Alder cycloaddition, Mannich, Horner-Wadsworth-Emmons and others. Research focuses on optimizing methods for obtaining chiral heteroorganic connections and their use as building blocks and in catalysis (as ligands in reactions involving metal ions or catalysts). An important research trend is the work on compounds showing the desired biological activity, e.g. antiproliferative or anti-viral.

Selected scientific articles

1
J. Iwanejko, M. Sowiński, E. Wojaczyńska, T. K. Olszewski and M. Górecki, An approach to new chiral bicyclic imines and amines via Horner–Wadsworth–Emmons reaction, RSC Adv., 2020, 10, 14618–14629. Cite
1
A. Łupicka-Słowik, M. Psurski, R. Grzywa, M. Cuprych, J. Ciekot, W. Goldeman, E. Wojaczyńska, J. Wojaczyński, J. Oleksyszyn and M. Sieńczyk, Structure-based design, synthesis, and evaluation of the biological activity of novel phosphoroorganic small molecule IAP antagonists, Invest New Drugs, , DOI:10.1007/s10637-020-00923-4. Cite
1
M. Samadaei, M. Pinter, D. Senfter, S. Madlener, N. Rohr-Udilova, D. Iwan, K. Kamińska, E. Wojaczyńska, J. Wojaczyński and A. Kochel, Synthesis and Cytotoxic Activity of Chiral Sulfonamides Based on the 2-Azabicycloalkane Skeleton, Molecules, 2020, 25, 2355. Cite
1
E. Wojaczyńska and J. Wojaczyński, Modern Stereoselective Synthesis of Chiral Sulfinyl Compounds, Chemical Reviews, , DOI:10.1021/acs.chemrev.0c00002. Cite
1
F. Steppeler, D. Iwan, E. Wojaczyńska and J. Wojaczyński, Chiral thioureas-preparation and significance in asymmetric synthesis and medicinal chemistry, Molecules, , DOI:10.3390/molecules25020401. Cite

Professional career

2019

Wroclaw University of Science and Technology — Associate Professor

  • Dean's Plenipotentiary for Promotion
2001 - 2019

Wroclaw University of Science and Technology — Assistant Professor

Titles and degrees

2014

Wroclaw University of Science and Technology — Faculty of Chemistry – D.Sc. (habilitation) in chemical sciences (organic chemistry)

2001

Wroclaw University of Science and Technology — Faculty of Chemistry – Ph.D. in chemical sciences (organic chemistry)

1997

Wroclaw University of Science and Technology — Faculty of Chemistry – M.Sc. in chemistry (chemical technology)

Scientific internships

2010-2020 - short-term training or research stays

University of Bristol, Cardiff University, University of Cagliari, University of Ferrara, University of Florence, University of Perugia, University of Rome (Tor Vergata), University of Madrid (UNED), University of Montpellier, University of Cluj-Napoca, Ege University (Izmir) and İstanbul University-Cerrahpaşa

2019 - two-week study visit

RK University i Marwadi University, Rajkot; Gujarat Technological University and SAL Education Campus, Ahmedabad; Parul University, Vadodara

Awards

Awarded many times for her scientific and organizational activities with the awards of the Rector of the Wrocław University of Science and Technology (2008, 2009, 2010, 2014, 2015, 2016, 2017, 2018, 2019). Reviewer of the ST4 panel of the National Science Center and articles for many scientific journals (including Journal of Organic Chemistry, Beilstein Journal of Organic Chemistry, New Journal of Chemistry, Tetrahedron Letters, Molecules, Catalysts, Symmetry). Reviewer of 10 doctoral dissertations.

Other key awards and functions:

2019 – vice-chairman of the Regional Committee for the Chemistry Olympiad;
2019 – Commemorative Medal of the Polish Chemical Society;
2018 – Medal of the National Education Committee;
2018 – Bronze Badge of the Wrocław University of Science and Technology;
2018 – facilitator of the special edition of the Arkivoc magazine;
since 2016 – chairwoman of the Wrocław Branch of the Polish Chemical Society;
since 2015 – assistant editor for the Chemical Papers journal;
2013-2014 – academic supervisor of students (M. Dorsz, M. Golimowska, K. Kleniewska) – winners
of Ventures grant from the Foundation for Polish Science;
since 2013 – deputy coordinator of the Lower Silesian Science Festival at the Wrocław University of Science and Technology;
2011 – Medal of the Century of the Wrocław University of Science and Technology;
since 2010 – member of the Regional Committee of the Chemistry Olympiad
since 2008 – coordinator of the Lower Silesian Science Festival at the Faculty of Chemistry of the Wrocław University of Science and Technology;
since 2008 – Faculty of Chemistry Dean’s Plenipotentiary for Promotion;
2002 – travel scholarship from the Foundation for Polish Science.

1
J. Iwanejko, M. Sowiński, E. Wojaczyńska, T. K. Olszewski and M. Górecki, An approach to new chiral bicyclic imines and amines via Horner–Wadsworth–Emmons reaction, RSC Adv., 2020, 10, 14618–14629. Cite
1
A. Łupicka-Słowik, M. Psurski, R. Grzywa, M. Cuprych, J. Ciekot, W. Goldeman, E. Wojaczyńska, J. Wojaczyński, J. Oleksyszyn and M. Sieńczyk, Structure-based design, synthesis, and evaluation of the biological activity of novel phosphoroorganic small molecule IAP antagonists, Invest New Drugs, , DOI:10.1007/s10637-020-00923-4. Cite
1
M. Samadaei, M. Pinter, D. Senfter, S. Madlener, N. Rohr-Udilova, D. Iwan, K. Kamińska, E. Wojaczyńska, J. Wojaczyński and A. Kochel, Synthesis and Cytotoxic Activity of Chiral Sulfonamides Based on the 2-Azabicycloalkane Skeleton, Molecules, 2020, 25, 2355. Cite
1
E. Wojaczyńska and J. Wojaczyński, Modern Stereoselective Synthesis of Chiral Sulfinyl Compounds, Chemical Reviews, , DOI:10.1021/acs.chemrev.0c00002. Cite
1
F. Steppeler, D. Iwan, E. Wojaczyńska and J. Wojaczyński, Chiral thioureas-preparation and significance in asymmetric synthesis and medicinal chemistry, Molecules, , DOI:10.3390/molecules25020401. Cite
1
A. Miniewicz, S. Bartkiewicz, E. Wojaczynska, T. Galica, R. Zalesny and R. Jakubas, Second harmonic generation in nonlinear optical crystals formed from propellane-type molecules, Journal of Materials Chemistry C, 2019, 7, 1255–1262. Cite
1
J. Iwanejko, A. Brol, B. M. Szyja, M. Daszkiewicz, E. Wojaczyńska and T. K. Olszewski, Aminophosphonates and aminophosphonic acids with tetrasubstituted stereogenic center: Diastereoselective synthesis from cyclic ketimines, Organic and Biomolecular Chemistry, 2019, 17, 7352–7359. Cite
1
J. Iwanejko, A. Brol, B. Szyja, M. Daszkiewicz, E. Wojaczyńska and T. K. Olszewski, Hydrophosphonylation of chiral hexahydroquinoxalin-2(1H)-one derivatives as an effective route to new bicyclic compounds: Aminophosphonates, enamines and imines, Tetrahedron, 2019, 75, 1431–1439. Cite
1
E. Wojaczyńska and A. Trochimczuk, Selenium-containing polymers: Synthesis and applications, Arkivoc, , DOI:10.24820/ark.5550190.p011.077. Cite
1
J. Iwanejko, E. Wojaczyńska and T. K. Olszewski, Green chemistry and catalysis in Mannich reaction, Current Opinion in Green and Sustainable Chemistry, 2018, 10, 27–34. Cite
1
J. Iwanejko and E. Wojaczyńska, Cyclic imines-preparation and application in synthesis, Organic and Biomolecular Chemistry, 2018, 16, 7296–7314. Cite
1
K. Kamińska, E. Wojaczyńska, J. Skarżewski, A. Kochel and J. Wojaczyński, Application of sulfonyl chlorides and chiral amines in the efficient synthesis of nonracemic sulfinamides, Tetrahedron Asymmetry, 2017, 28, 561–566. Cite
1
K. Kamińska, E. Wojaczyńska, C. Santi, L. Sancineto, M. Francesca Pensa, A. Kochel, R. Wieczorek, J. Wojaczyński and G. Slupski, An enantiopure diselenide based on a chiral bicyclic backbone—synthesis and configuration assignment, Tetrahedron Asymmetry, 2017, 28, 1367–1372. Cite
1
J. Iwanejko, E. Wojaczyńska, J. Trynda, M. Maciejewska, J. Wietrzyk, A. Kochel and J. Wojaczyński, New chiral Mannich adducts of di-tert-butylphenols and a bicyclic imine – Synthesis and antiproliferative activity, Tetrahedron, 2017, 73, 2276–2282. Cite
1
K. Kamińska, E. Wojaczyńska, J. Wietrzyk, E. Turlej, A. Błażejczyk and R. Wieczorek, Synthesis, structure and antiproliferative activity of chiral polyamines based on a 2-azanorbornane skeleton, Tetrahedron Asymmetry, 2016, 27, 753–758. Cite
1
E. Wojaczyńska, K. Kamińska, J. Wojaczyński and J. Skarzewski, Chiral pyrrolidine thioethers and 2-azanorbornane derivatives bearing additional nitrogen functions. Enantiopure ligands for palladium-catalyzed Tsuji-Trost reaction, Arkivoc, 2016, 2017, 162–172. Cite
1
E. Wojaczyńska, J. Skarżewski, Ł. Sidorowicz, R. Wieczorek and J. Wojaczyński, Zinc complexes formed by 2,2′-bipyridine and 1,10-phenanthroline moieties combined with 2-azanorbornane: Modular chiral catalysts for aldol reactions, New Journal of Chemistry, 2016, 40, 9795–9805. Cite
1
M. Dorsz, K. Kleniewska and E. Wojaczyńska, Monoimines derived from (1 R,2 R)-1,2-diaminocyclohexane in aza-Diels-Alder reaction: Synthesis and characterization of sulfur derivatives based on the 2-azanorbornyl skeleton, Phosphorus, Sulfur and Silicon and the Related Elements, 2016, 191, 279–282. Cite
1
T. K. Olszewski, E. Wojaczyńska, R. Wieczorek and J. Bąkowicz, α-Hydroxyphosphonic acid derivatives of 2-azanorbornane: Synthesis, DFT calculations, and crystal structure analysis, Tetrahedron Asymmetry, 2015, 26, 601–607. Cite
1
E. Wojaczyńska, J. Wojaczyński, K. Kleniewska, M. Dorsz and T. K. Olszewski, 2-Azanorbornane-a versatile chiral aza-Diels-Alder cycloadduct: Preparation, applications in stereoselective synthesis and biological activity, Organic and Biomolecular Chemistry, 2015, 13, 6116–6148. Cite
1
J. Iwanejko, E. Wojaczyńska, J. Wojaczyński and J. Bąkowicz, Stereoselective preparation of chiral compounds in Mannich-type reactions of a bicyclic imine and phenols or indole Dedicated to Professor Jacek Skarzewski on the occasion of his 65th birthday, Tetrahedron Letters, 2014, 55, 6619–6622. Cite
1
E. Wojaczyńska, J. Baì̈kowicz, M. Dorsz and J. Skarzìewski, Monoimine derived from trans-1,2-diaminocyclohexane and ethyl glyoxylate: An intermediate in aza-Diels-Alder and Mannich reactions, Journal of Organic Chemistry, 2013, 78, 2808–2811. Cite
1
E. Wojaczyńska and I. Turowska-Tyrk, Autoxidation of a tetracyclic lactam and its conversion to an enantiopure tertiary alcohol, Tetrahedron Asymmetry, 2013, 24, 1247–1251. Cite
1
E. Wojaczyńska, I. Turowska-Tyrk and J. Skarzewski, Novel chiral bridged azepanes: Stereoselective ring expansion of 2-azanorbornan-3-yl methanols, Tetrahedron, 2012, 68, 7848–7854. Cite
1
A. E. Nowak, E. Wojaczyńska and J. Skarewski, Enantiopure trans-1-amino-2-(arylsulfanyl)cyclohexanes: Novel chiral motifs for ligands and organocatalysts, Tetrahedron Asymmetry, 2011, 22, 1687–1691. Cite
1
E. Wojaczyńska, New 2-azanorbornyl derivatives: Chiral (N,N)-donating ligands for asymmetric catalysis, Tetrahedron Asymmetry, 2011, 22, 161–166. Cite
1
E. Wojaczyńska and J. Wojaczyński, Enantioselective synthesis of sulfoxides: 2000-2009, Chemical Reviews, 2010, 110, 4303–4356. Cite
1
E. Wojaczyńska, M. Zielińska-Błajet, I. Turowska-Tyrk and J. Skarzewski, Sulfoxides derived from Cinchona alkaloids - Chiral ligands in palladium-catalyzed asymmetric allylic alkylation, Tetrahedron Asymmetry, 2010, 21, 853–858. Cite
1
E. Wojaczyńska and J. Skarzewski, An effective deracemization of trans-1,2-bis (phenylsulfenyl)cyclohexane, Phosphorus, Sulfur and Silicon and the Related Elements, 2009, 184, 1323–1331. Cite
1
E. Wojaczyńska and J. Skarzewski, Novel C2-symmetric chiral ligands: enantioselective transformation of cyclic 1,2-diols into 1,2-bis(phenylsulfenyl) and 1,2-bis(phenylselenyl) derivatives, Tetrahedron Asymmetry, 2008, 19, 593–597. Cite
1
P. Kwiatkowski, E. Wojaczyńska and J. Jurczak, Asymmetric Friedel-Crafts reaction of furans with alkyl glyoxylates catalyzed by (salen)Co(II) complexes, Journal of Molecular Catalysis A: Chemical, 2006, 257, 124–131. Cite
1
R. Siedlecka, E. Wojaczyńska and J. Skarzewski, Chiral pyrrolidine thioethers: Effective nitrogen-sulfur donating ligands in palladium-catalyzed asymmetric allylic alkylations, Tetrahedron Asymmetry, 2004, 15, 1437–1444. Cite
1
J. Skarzewski, A. Gupta, E. Wojaczyńska and R. Siedlecka, One-step, enantiospecific transformation of cyclic, five-membered-1, 2-diols into their respective 1,2-bis(phenylsulfanyl) derivatives, Synlett, 2003, 1615–1618. Cite
1
P. Kwiatkowski, E. Wojaczyńska and J. Jurczak, (Salen)Co(II) complex - An efficient catalyst for the high-pressure Friedel-Crafts reaction of 2-methylfuran with alkyl glyoxylates, Tetrahedron Asymmetry, 2003, 14, 3643–3645. Cite
1
J. Skarżewski, R. Siedlecka, E. Wojaczyńska and M. Zielińska-Blajet, A new and efficient route to homochiral γ-hydroxysulfoxides and γ-hydroxysulfones, Tetrahedron Asymmetry, 2002, 13, 2105–2111. Cite
1
J. Skarżewski, E. Wojaczyńska and I. Turowska-Tyrk, Sequential asymmetric dihydroxylation and sulfoxidation of homoallylic sulfides. Stereochemical aspects of the preparation of new trifunctional chiral building blocks, Tetrahedron Asymmetry, 2002, 13, 369–375. Cite