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Szukaj

Dr hab. inż. Elżbieta Wojaczyńska

Profesor Uczelni, Pełnomocnik Dziekana ds. Promocji Wydziału Chemicznego

Wybrzeże Wyspiańskiego 27

50-370 Wrocław

elzbieta.wojaczynska@pwr.edu.pl

(+48) 71 320 2410

Office:Budynek A02, p. 219

Curriculum vitae
Bibliografia
Do pobrania

Zainteresowania naukowe

Chemia organiczna, w szczególności synteza stereoselektywna układów mono- i poliheterocyklicznych na drodze cykloaddycji hetero-Dielsa-Aldera, reakcji Mannicha, Hornera-Wadswortha-Emmonsa i innych. Badania koncentrują się na optymalizacji metod otrzymywania chiralnych połączeń heteroorganicznych i ich zastosowaniu w charakterze bloków budulcowych oraz w katalizie (jako ligandy w reakcjach z udziałem jonów metali lub katalizatory). Istotnym nurtem badawczym jest praca nad związkami wykazującymi pożądaną aktywność biologiczną, na przykład antyproliferacyjną czy antywirusową.

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J. Iwanejko, M. Sowiński, E. Wojaczyńska, T. K. Olszewski and M. Górecki, An approach to new chiral bicyclic imines and amines via Horner–Wadsworth–Emmons reaction, RSC Adv., 2020, 10, 14618–14629. Cite
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A. Łupicka-Słowik, M. Psurski, R. Grzywa, M. Cuprych, J. Ciekot, W. Goldeman, E. Wojaczyńska, J. Wojaczyński, J. Oleksyszyn and M. Sieńczyk, Structure-based design, synthesis, and evaluation of the biological activity of novel phosphoroorganic small molecule IAP antagonists, Invest New Drugs, , DOI:10.1007/s10637-020-00923-4. Cite
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M. Samadaei, M. Pinter, D. Senfter, S. Madlener, N. Rohr-Udilova, D. Iwan, K. Kamińska, E. Wojaczyńska, J. Wojaczyński and A. Kochel, Synthesis and Cytotoxic Activity of Chiral Sulfonamides Based on the 2-Azabicycloalkane Skeleton, Molecules, 2020, 25, 2355. Cite
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Kariera

2019 - OBECNIE

Politechnika Wrocławska — Profesor Uczelni

  • Pełnomocnik Dziekana ds. Promocji Wydziału Chemicznego
2001 - 2019

Politechnika Wrocławska — Adiunkt z habilitacją

Tytuły i stopnie

2014

Politechnika Wrocławska — Wydział Chemiczny – stopień dr. hab. nauk chemicznych (chemia organiczna)

2001

Politechnika Wrocławska — Wydział Chemiczny – stopień dr. nauk chemicznych (chemia organiczna)

1997

Politechnika Wrocławska — Wydział Chemiczny – tytuł mgr. inż. chemii (technologia chemiczna)

Staże naukowe

2010-2020 - krótkoterminowe pobyty szkoleniowe i naukowe

University of Bristol, Cardiff University, University of Cagliari, University of Ferrara, University of Florence, University of Perugia, University of Rome (Tor Vergata), University of Madrid (UNED), University of Montpellier, University of Cluj-Napoca, Ege University (Izmir) oraz İstanbul University-Cerrahpaşa. — Montpellier, Francja – visiting professor

2019 - dwutygodniowa wizyta studyjna w Indiach

RK University i Marwadi University, Rajkot; Gujarat Technological University oraz SAL Education Campus, Ahmedabad; Parul University, Vadodara — School of Chemistry, Cardiff, Walia, UK – visiting professor

Nagrody

Wielokrotnie nagradzana za działalność naukową i organizacyjną nagrodami Rektora Politechniki Wrocławskiej (2008, 2009, 2010, 2014, 2015, 2016, 2017, 2018, 2019). Recenzent panelu ST4 Narodowego Centrum Nauki oraz artykułów dla wielu czasopism naukowych (m.in. Journal of Organic Chemistry, Beilstein Journal of Organic Chemistry, New Journal of Chemistry, Tetrahedron Letters, Molecules, Catalysts, Symmetry). Recenzent w 10 zakończonych przewodach doktorskich.

Inne najważniejsze wyróżnienia i funkcje:

od 2019 wiceprzewodnicząca Komitetu Okręgowego Olimpiady Chemicznej;
2019 – Medal Okolicznościowy Polskiego Towarzystwa Chemicznego;
2018 – Medal Komisji Edukacji Narodowej;
2018 – Brązowa Odznaka Politechniki Wrocławskiej;
2018 – facilitator specjalnej edycji czasopisma Arkivoc;
od 2016 – przewodnicząca Oddziału Wrocławskiego Polskiego Towarzystwa Chemicznego;
od 2015 – edytor pomocniczy w czasopiśmie Chemical Papers;
2013-2014 opiekun naukowy studentów (M. Dorsz, M. Golimowska, K. Kleniewska) – laureatów grantu Ventures Fundacji Na Rzecz Nauki Polskiej;
od 2013 – zastępca Koordynatora Dolnośląskiego Festiwalu Nauki na Politechnice Wrocławskiej;
2011 – Medal Stulecia Politechniki Wrocławskiej;
od 2010 – członek Komitetu Okręgowego Olimpiady Chemicznej;
od 2008 – koordynator Dolnośląskiego Festiwalu Nauki na Wydziale Chemicznym Politechniki Wrocławskiej;
od 2008 – pełnomocnik Dziekana Wydziału Chemicznego ds. Promocji;
2002 – stypendium wyjazdowe Fundacji na rzecz Nauki Polskiej;

415588 UL3NK4XX 1 royal-society-of-chemistry-with-titles 50 date desc year 1 title 1094 https://huckel.pl/wp-content/plugins/zotpress/
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J. Iwanejko, E. Wojaczyńska and T. K. Olszewski, Green chemistry and catalysis in Mannich reaction, Current Opinion in Green and Sustainable Chemistry, 2018, 10, 27–34. Cite
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J. Iwanejko and E. Wojaczyńska, Cyclic imines-preparation and application in synthesis, Organic and Biomolecular Chemistry, 2018, 16, 7296–7314. Cite
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K. Kamińska, E. Wojaczyńska, J. Skarżewski, A. Kochel and J. Wojaczyński, Application of sulfonyl chlorides and chiral amines in the efficient synthesis of nonracemic sulfinamides, Tetrahedron Asymmetry, 2017, 28, 561–566. Cite
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K. Kamińska, E. Wojaczyńska, C. Santi, L. Sancineto, M. Francesca Pensa, A. Kochel, R. Wieczorek, J. Wojaczyński and G. Slupski, An enantiopure diselenide based on a chiral bicyclic backbone—synthesis and configuration assignment, Tetrahedron Asymmetry, 2017, 28, 1367–1372. Cite
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J. Iwanejko, E. Wojaczyńska, J. Trynda, M. Maciejewska, J. Wietrzyk, A. Kochel and J. Wojaczyński, New chiral Mannich adducts of di-tert-butylphenols and a bicyclic imine – Synthesis and antiproliferative activity, Tetrahedron, 2017, 73, 2276–2282. Cite
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K. Kamińska, E. Wojaczyńska, J. Wietrzyk, E. Turlej, A. Błażejczyk and R. Wieczorek, Synthesis, structure and antiproliferative activity of chiral polyamines based on a 2-azanorbornane skeleton, Tetrahedron Asymmetry, 2016, 27, 753–758. Cite
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E. Wojaczyńska, K. Kamińska, J. Wojaczyński and J. Skarzewski, Chiral pyrrolidine thioethers and 2-azanorbornane derivatives bearing additional nitrogen functions. Enantiopure ligands for palladium-catalyzed Tsuji-Trost reaction, Arkivoc, 2016, 2017, 162–172. Cite
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E. Wojaczyńska, J. Skarżewski, Ł. Sidorowicz, R. Wieczorek and J. Wojaczyński, Zinc complexes formed by 2,2′-bipyridine and 1,10-phenanthroline moieties combined with 2-azanorbornane: Modular chiral catalysts for aldol reactions, New Journal of Chemistry, 2016, 40, 9795–9805. Cite
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M. Dorsz, K. Kleniewska and E. Wojaczyńska, Monoimines derived from (1 R,2 R)-1,2-diaminocyclohexane in aza-Diels-Alder reaction: Synthesis and characterization of sulfur derivatives based on the 2-azanorbornyl skeleton, Phosphorus, Sulfur and Silicon and the Related Elements, 2016, 191, 279–282. Cite
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T. K. Olszewski, E. Wojaczyńska, R. Wieczorek and J. Bąkowicz, α-Hydroxyphosphonic acid derivatives of 2-azanorbornane: Synthesis, DFT calculations, and crystal structure analysis, Tetrahedron Asymmetry, 2015, 26, 601–607. Cite
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E. Wojaczyńska, J. Wojaczyński, K. Kleniewska, M. Dorsz and T. K. Olszewski, 2-Azanorbornane-a versatile chiral aza-Diels-Alder cycloadduct: Preparation, applications in stereoselective synthesis and biological activity, Organic and Biomolecular Chemistry, 2015, 13, 6116–6148. Cite
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J. Iwanejko, E. Wojaczyńska, J. Wojaczyński and J. Bąkowicz, Stereoselective preparation of chiral compounds in Mannich-type reactions of a bicyclic imine and phenols or indole Dedicated to Professor Jacek Skarzewski on the occasion of his 65th birthday, Tetrahedron Letters, 2014, 55, 6619–6622. Cite
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E. Wojaczyńska, J. Baì̈kowicz, M. Dorsz and J. Skarzìewski, Monoimine derived from trans-1,2-diaminocyclohexane and ethyl glyoxylate: An intermediate in aza-Diels-Alder and Mannich reactions, Journal of Organic Chemistry, 2013, 78, 2808–2811. Cite
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E. Wojaczyńska and I. Turowska-Tyrk, Autoxidation of a tetracyclic lactam and its conversion to an enantiopure tertiary alcohol, Tetrahedron Asymmetry, 2013, 24, 1247–1251. Cite
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E. Wojaczyńska, I. Turowska-Tyrk and J. Skarzewski, Novel chiral bridged azepanes: Stereoselective ring expansion of 2-azanorbornan-3-yl methanols, Tetrahedron, 2012, 68, 7848–7854. Cite
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A. E. Nowak, E. Wojaczyńska and J. Skarewski, Enantiopure trans-1-amino-2-(arylsulfanyl)cyclohexanes: Novel chiral motifs for ligands and organocatalysts, Tetrahedron Asymmetry, 2011, 22, 1687–1691. Cite
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E. Wojaczyńska, New 2-azanorbornyl derivatives: Chiral (N,N)-donating ligands for asymmetric catalysis, Tetrahedron Asymmetry, 2011, 22, 161–166. Cite
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E. Wojaczyńska and J. Wojaczyński, Enantioselective synthesis of sulfoxides: 2000-2009, Chemical Reviews, 2010, 110, 4303–4356. Cite
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E. Wojaczyńska, M. Zielińska-Błajet, I. Turowska-Tyrk and J. Skarzewski, Sulfoxides derived from Cinchona alkaloids - Chiral ligands in palladium-catalyzed asymmetric allylic alkylation, Tetrahedron Asymmetry, 2010, 21, 853–858. Cite
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E. Wojaczyńska and J. Skarzewski, An effective deracemization of trans-1,2-bis (phenylsulfenyl)cyclohexane, Phosphorus, Sulfur and Silicon and the Related Elements, 2009, 184, 1323–1331. Cite
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E. Wojaczyńska and J. Skarzewski, Novel C2-symmetric chiral ligands: enantioselective transformation of cyclic 1,2-diols into 1,2-bis(phenylsulfenyl) and 1,2-bis(phenylselenyl) derivatives, Tetrahedron Asymmetry, 2008, 19, 593–597. Cite
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P. Kwiatkowski, E. Wojaczyńska and J. Jurczak, Asymmetric Friedel-Crafts reaction of furans with alkyl glyoxylates catalyzed by (salen)Co(II) complexes, Journal of Molecular Catalysis A: Chemical, 2006, 257, 124–131. Cite
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R. Siedlecka, E. Wojaczyńska and J. Skarzewski, Chiral pyrrolidine thioethers: Effective nitrogen-sulfur donating ligands in palladium-catalyzed asymmetric allylic alkylations, Tetrahedron Asymmetry, 2004, 15, 1437–1444. Cite
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J. Skarzewski, A. Gupta, E. Wojaczyńska and R. Siedlecka, One-step, enantiospecific transformation of cyclic, five-membered-1, 2-diols into their respective 1,2-bis(phenylsulfanyl) derivatives, Synlett, 2003, 1615–1618. Cite
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P. Kwiatkowski, E. Wojaczyńska and J. Jurczak, (Salen)Co(II) complex - An efficient catalyst for the high-pressure Friedel-Crafts reaction of 2-methylfuran with alkyl glyoxylates, Tetrahedron Asymmetry, 2003, 14, 3643–3645. Cite
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J. Skarżewski, R. Siedlecka, E. Wojaczyńska and M. Zielińska-Blajet, A new and efficient route to homochiral γ-hydroxysulfoxides and γ-hydroxysulfones, Tetrahedron Asymmetry, 2002, 13, 2105–2111. Cite
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J. Skarżewski, E. Wojaczyńska and I. Turowska-Tyrk, Sequential asymmetric dihydroxylation and sulfoxidation of homoallylic sulfides. Stereochemical aspects of the preparation of new trifunctional chiral building blocks, Tetrahedron Asymmetry, 2002, 13, 369–375. Cite